產品編號：Y0698

英文名稱：Ivermectine

CAS號 70288-86-7

分析標準品

分子式 C48H74O14 分子量875.09

基本信息:

存貯條件儲存溫度 2-8°C

描述

產品介紹穩定，在水中溶解度極低。

別名MK-933;MK-933;22,23-Dihydroavermectin B1

生化機理

Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine. Ivermectin is positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Ivermectin also modulates glutamate- and GABA-activated chloride channels. Ivermectin potentiates glycine-gated currents at low concentrations (30 nM).

應用Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.