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FITC標記的肌萎縮側索硬化癥相關蛋白3抗體

文字:[大][中][小] 2017-5-2    瀏覽次數:1212    

                                     FITC標記的肌萎縮側索硬化癥相關蛋白3抗體                                                                                                                                                
英文名稱Anti-ALS2CR3/FITC
中文名稱:FITC標記的肌萎縮側索硬化癥相關蛋白3抗體
別    名ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.  

詳細介紹:


規格:100ul 
說 明 書100ul  
研究領域細胞生物  神經生物學  Alzheimer's  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
產品應用ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量101kDa
性    狀Lyophilized or Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ALS2CR3 (701-800aa)
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關資料:


產品介紹background:
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR

Function:
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR 

Subunit:
Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2.

Subcellular Location:
Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner

Tissue Specificity:
Widely expressed, with highest expression in heart.

Post-translational modifications:
O-glycosylated

Similarity:
Contains 1 HAP1 N-terminal domain.

Database links:
UniProtKB/Swiss-Prot: O60296.2

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